This Day in Missouri History Largest Colleges in Missouri / Comments Off on Largest Colleges in Missouri Largest Colleges in Missouri:1 University of Missouri-Columbia 38,022 2 Saint Louis Community Colleges 34,766 3 Columbia College 29,317 4 Metropolitan Community College-KC 28,160 5 Missouri State University-Springfield 24,747 6 Webster University 22,850 7 University of Missouri-St Louis 20,988 8 University of Missouri-Kansas City 20,502 9 Saint Louis University 20,106 10 Ozarks Technical Community College 19,793FacebookTweetPinLinkedIn